Morphokinetic Cellular Analysis

E. coli vs. Pip-Tazo
MIC = 2
Susceptible
MIC = 2
Susceptible

E. coli vs. Ceftazidime
MIC = 32
Resistant
MIC = 32
Resistant
E. coli vs. Pip-Tazo
MIC = 2
Susceptible
MIC = 2
Susceptible
E. coli vs. Ceftazidime
MIC = 32
Resistant
MIC = 32
Resistant
The difference is
in the details.
Tracking & Capturing
- Studying and identifying individual cells and colonies
- Recording division, growth patterns and other changes in cells
- Capturing massive amounts of morphokinetic data
Generating & Analyzing
- Reviewing ratio of number of clones to growth control
- Generating profiles that include growth probability and time
- Evaluating response profiles
- Identifying and analyzing patterns
- Identification of susceptible vs. resistant cells
Interpreting
- Interpreting results
- Delivering actionable information
- Generate MIC with customizable breakpoints
Future possibilities
- Heterogeneity
- Pharmacodynamics
- Bacteriocidality